Analyser of structural variants of chromosomes Saphyr

Reveal genome-wide structural variation with the Saphyr™ optical genome mapping system.

 

Empower your lab with advanced SV detection using optical genome mapping.

 

Routinely detect all classes of structural variants down to 500 base pair (bp) resolution and 5% variant allele frequency (VAF) with optical genome mapping (OGM) using the Saphyr™ system. Saphyr™ is the most powerful structural variant detection tool available, detecting genomic variants commonly missed by next-generation sequencing (NGS) technologies and conventional cytogenetic techniques.

 

The Saphyr™ system provides optical genome mapping of ultra-high molecular weight (UHMW) DNA in its native state, from molecules 150 kbp to multi-megabase pairs in length.

 

Achieve broad, unbiased genomic coverage with flexible data collection.

 

The genomic coverage achieved with the Saphyr™ system is flexible and allows for the detection of heterozygous variants or rarer variants found in mosaic samples and heterogeneous tumors.

 

Collect 100X coverage of a human genome in as little as six hours. See deeper and rarer variants by simply extending the data collection time on Saphyr™ at no additional consumables cost. Achieve 400X coverage in 24 hours and provide SV detection down to 5% VAF. Further extend runs to see even lower VAF.

 

Experience seamless integration and workflow using the Saphyr™ Chip^® consumable and Saphyr™ system.

 

The Saphyr Chips utilize hundreds of thousands of massively parallel nanochannels that linearize long, labeled DNA molecules, allowing the Saphyr instrument to directly image your samples.

 

Sample loading on the Saphyr Chip is fast and easy. Pipet up to three samples into individual flow cells on the chip. Load up to two chips onto the Saphyr instrument per run for a maximum throughput of six samples per run.