Atellica NEPH 630 System

The Atellica NEPH 630 System is a nephelometric analyser that simplifies the analysis of specific proteins in the laboratory. The system features a broad menu of protein assays for laboratory testing of plasma and serum, urine, cerebrospinal fluid and provides advanced evaluation of a range of diseases. With innovative assays such as immunoglobulin light chain assays, Carbohydrate-Deficient Transferrin (CDT) and others, the system allows you to assess and monitor your risk of cardiovascular disease, kidney disease, neurological disorders, chronic alcohol dependence and more.

 

• Expand your capabilities with an extensive menu of protein analyses for different sample types.
• Reduce time spent on manual activities so your lab staff can focus on more important tasks.
• Optimise your lab workflows with highly intelligent software and connectivity to information systems.
• Get accurate and reliable assay results with protection against excessive antigen levels.
• Save time and reduce waste with continuous access and intelligent technology.
• Empower clinicians to improve patient outcomes.
   

Features

 

Expand your testing capabilities with an extensive protein analysis menu for multiple sample types
 

• The industry's largest assay menu for nephelometric plasma protein assays with over 60 test protocols.
• Innovative assays including immunoglobulin light chain and Carbohydrate-Deficient Transferrin (CDT) assays.
• Extensive diagnostic capabilities, including cardiovascular disease risk, kidney disease, neurological disorders, dietary nutritional value, iron metabolism and anaemia levels, etc.

 

Reduce time spent on manual activities so lab staff can focus on more important tasks
 

• Flexible use of different sample types in random access mode makes working with the system more convenient.
• On-board storage of reagents and controls ensures continuous (24/7) operation, long-term reagent stability and minimal operator intervention.
• High sample loading capacity allows for load-and-go operation.
• The use of a barcode on the primary sample tube minimises manual handling and prevents sample mix-ups.
• Automatic dilutions and re-measurement of samples with out-of-range results (with values above or below the acceptable range) are performed without operator intervention.

 

Optimise your work processes with highly intelligent software and connectivity to information systems.
 

• Siemens Remote Support (SRS) identifies and diagnoses potential equipment problems, providing immediate technical intervention and rapid troubleshooting.
• Integration with Atellica PM software simplifies lab operations by aggregating system data, alarms, remote monitoring capabilities of the Atellica NEPH 630 system and other connected instruments on a single screen.
• The CentraLink data management system allows standardised management of protocols and analysis results.

Get accurate and reliable results
 

• Proven nephelometric technology ensures high accuracy and reproducibility.
  Sophisticated pre-reaction protocols for antigen excess provide more accurate results and fewer repeats.
• Wide initial measurement ranges reduce the need for repeat analyses.
• The system determines sample and reagent levels prior to processing to ensure accurate results.
• Graphical display of kinetic curves provides additional information and improves troubleshooting.
• State-of-the-art software provides a high level of cybersecurity.

 

Save time and reduce waste with continuous access and intelligent technology
 

• Flexible sample dilution and automatic repeat assay functions can often be performed without re-accessing the primary sample.
• High average throughput of approximately 65 analyses per hour depending on the combination of analyses. Nominal throughput is 100 analyses per hour.
• Sophisticated sample dilution function allows rapid addition of assays or reanalysis of samples.
• Samples and reagents can be loaded and reloaded at any time without stopping the analyses.
   

Analysis

Polyclonal and monoclonal gammopathy/Immune system 
β2-Microglobulin 
Ig/lung kappa chain
Ig/lung lambda chain
IgA 
IgG 
IgG subclasses 1-4 
IgM
 

Kidney disease
α1-microglobulin in urine
α2-macroglobulin in urine 
β2-microglobulin in urine 
Urinary albumin 
Cystatin C in serum 
Ig/lung kappa chain in urine 
Ig/light lambda chain in urine 
IgG in urine 
Transferrin in urine

 

Inflammation 
α1-acid glycoprotein 
High-sensitivity C-reactive protein 
Fibrinogen 
Serum amyloid A
 

Autoimmune and rheumatoid diseases 
Anti-DNase B 
ASL (anti-streptolysin) 
C3c 
C4 
Highly sensitive C-reactive protein
Rheumatoid factor

 
Cardiovascular risk/
Intensive care in cardiology 
Albumin in urine 
Apo A-I (apolipoprotein A-I) 
Apo B (apolipoprotein B) 
Cystatin C 
Fibrinogen 
High-sensitivity C-reactive protein
Homocysteine 
Lp(α) (lipoprotein α) 
Myoglobin
 

Chronic alcoholism 
CDT (carbohydrate-deficient transferrin) 
Transferrin (to calculate %CDT)

 
Allergic diseases 
IgE (immunoglobulin E)

 
Assessment of the nutritional value of the diet
Albumin
C-reactive protein
Ferritin
Prealbumin
RBP (retinol-binding protein)

 
Blood coagulation disorders
Antithrombin III
Fibrinogen
Plasminogen
 

Anaemia/iron metabolism
Ferritin
Haptoglobin
Haemopexin
sTfR (soluble transferrin receptor)
Transferrin

 
Complement system activity
C1 esterase inhibitor
C3c
C4

 
Disruption of blood-CMJ barrier function
Albumin
Albumin in CSF
IgA
IgA in CSF
IgG
IgG in CSF
IgM
IgG in CSF
 

Tests for other special analyses
α1-antitrypsin
α2-macroglobulin in serum
Apo A-II (apolipoprotein A-II)
Apo E (apolipoprotein E)
Ceruloplasmin
Fibronectin