Nanoparticle Measurement System Pulsoid

Pulsoid is an innovative high-precision nanoparticle measurement system based on Nanopore Pulse Sensing (NPS) technology. The instrument provides direct, single-particle analysis of size, concentration, and zeta potential with TEM-level accuracy and high throughput.

 

High-Resolution Single-Particle Analysis

 

Pulsoid performs single-particle analysis, enabling detection of heterogeneity and particle subpopulations that are not identified by ensemble methods (e.g., DLS).

 

TEM-Level Size Accuracy

 

Size measurement accuracy up to 100% ±2%, with 99.7% agreement compared to TEM (for NIST-traceable standards).

 

Direct Particle Counting

 

Concentration is determined by direct counting of each individual particle, ensuring a linear response across a wide concentration range.

 

Simultaneous Zeta Potential Measurement

 

Pulsoid simultaneously measures particle size and zeta potential on a particle-by-particle basis, enabling detailed analysis of surface charge and formulation stability.

 

Solid-State Silicon Nanopore Chip

 

The system is built around a precision-manufactured silicon nanopore chip with fixed pore geometry, providing:

• Signal stability

• High reproducibility

• Minimal calibration requirements

• Easy cleaning

 

Optimised for LNP

 

The system is designed for the analysis of:

• Lipid nanoparticles (LNP)

• Exosomes

• Virus-like particles

• Polymeric nanoparticles

 

Laboratory Benefits

 

1. Sample analysis in 2–5 minutes
2. High throughput
3. Reduced user error risk
4. Simple setup and short training time