Toxicological Analyzer

Toxicological analysis is a complex of chemical-toxicological studies aimed at the quantitative detection of medicinal and narcotic substances in the body.

 

One of the best methods for conducting such studies today is multienzyme immunochemistry (EMIT), which provides a test of samples for suitability and guarantees exceptional accuracy and reliability of the results obtained. The basis of the method is the principle of competitive binding, where the analyte (substance to be determined) and its analogue, associated with an enzyme marker, compete for binding to a limited number of specific antibodies. The uniqueness of EMIT lies in the use of a multienzyme approach: several different enzyme markers are used, each of which is associated with an analogue of a different substance. This allows the simultaneous determination of concentrations of several analytes in one sample, which saves time and reagents. This approach is especially useful for monitoring drug levels, for example, during chemotherapy or immunosuppressive therapy after transplantation. For example, the method allows simultaneous monitoring of cyclosporine and tacrolimus levels in patients after kidney transplantation.

 

Main types

 

There are several types of toxicological analyzers used for various studies:

 

1. Mass spectrometers. This is a toxicological analyzer that allows for very accurate studies of the presence of toxic and narcotic substances at the molecular level.
2. Toxicometers. Toxicological analyzer for detecting narcotic and psychotropic substances in various biological environments, for example, in saliva.

 

Toxicological analyzer - principles of application

 

The medical device is used in many areas. Its main application:

 

• In oncology and organ transplantation. Widely used to determine the level of methotrexate, tacrolimus, cyclosprin, and other highly toxic substances used to treat various oncological diseases. To control immunological reactions of rejection during organ and tissue transplantation is one of the most serious problems affecting the quality of treatment, life, and survival of patients. To analyze the effectiveness of immunosuppressive therapy in the post-transplant period.
• Drug clinics. Detection of narcotic and psychotropic substances in biological samples (blood, urine, saliva) helps in establishing an accurate diagnosis and planning treatment for addictions.
• Toxicology laboratories. In such laboratories, detailed studies are conducted using analyzers to detect the presence of toxic compounds in various environments, which makes it possible to assess the degree of environmental or food contamination.

 

You can buy an analyzer for the content of chemicals in the body in the Empirica online store at an affordable price and with delivery across Ukraine.