Kit for detection of RhD antigen (RHD)

Fetal RHD genotyping from maternal blood allows targeted anti-D prophylaxis in RhD-negative pregnant women without anti-D alloimmunization, avoiding unnecessary exposure to anti-D immunoglobulin.

 

Key Features

 

• Specific – Sensitive – Reliable – Robust

 

• Applicable from gestation week 12

 

• All-in-one CE-IVD kit (submitted for IVDR certification)

 

• Multiplex amplification and detection of human RHD gene exons 5, 7, and 10

 

• Detection of RHD variants possible due to multiplex format

 

• Internal Positive Control (IPC) system to exclude false-negative results using a short synthetic DNA fragment (<120 bp) imitating circulating fetal DNA

 

• Rapid hot-start Taq DNA polymerase

 

FetoGnost® Kit Control (RUO)

 

• For validation of extraction methods

 

• Kit for detection of cell-free fetal DNA (cffDNA)

 

• Amplification and detection of one maternal DNA marker and two fetal DNA markers

 

• Restriction enzyme digestion system included